Is er een product dat kaolien zwaar kan vervangen in de bereiding van een siroop tegen diarree?

Veegum (alumunium magnesiumsilicaat) heeft net als kaolien (gehydrateerd aluminiumsilicaat) adsorberende eigenschappen (in concentratie 10-50%), maar heeft als nadeel dat in orale suspensies (0,5-2,5%) een negatieve invloed kan hebben op de vrijstelling van bepaalde geneesmiddelen.

Adsorberende kool heeft eveneens adsorberende eigenschappen. Hierbij vermeldt de Martindale het volgende: “Activated charcoal is most commonly given as a slurry in water but this is often unpalatable because of the colour, gritty taste, lack of flavour, and difficulty in swallowing. Flavourings and other excipients are often added in an attempt to improve palatability, although the effect of any additives on the adsorptive capacity of charcoal needs to be considered. Studies in vitro or in healthy subjects indicated that some foods such as ice cream, milk, and cocoa might inhibit the adsorptive capacity of activated charcoal, whereas starches and jams appeared to have no effect. Carmellose has improved palatability although it might also reduce adsorptive capacity. Saccharin sodium, sucrose, or sorbitol may be suitable additives, although there may be problems associated with sorbitol-containing products (see under Poisoning, Activated Charcoal). Chocolate syrup has also been used but the sweetness and flavour may disappear after a few minutes of contact with the activated charcoal. The BNFC suggests that activated charcoal suspension may be mixed with soft drinks such as caffeine-free diet cola or fruit juices to mask the taste. A more recent study of charcoal use in children with suspected poisoning found no evidence that use of flavourings improved the success of administration”