{"id":60359,"date":"2025-02-25T16:30:34","date_gmt":"2025-02-25T15:30:34","guid":{"rendered":"https:\/\/fagroncompoundingservices.be\/qanda\/is-amitriptylinehydrochloride-stabiel-in-pentravan-wat-is-de-bereidingswijze\/"},"modified":"2025-02-25T16:30:34","modified_gmt":"2025-02-25T15:30:34","slug":"is-amitriptylinehydrochloride-stabiel-in-pentravan-wat-is-de-bereidingswijze","status":"publish","type":"qanda","link":"https:\/\/fagroncompoundingservices.be\/fr\/qanda\/is-amitriptylinehydrochloride-stabiel-in-pentravan-wat-is-de-bereidingswijze\/","title":{"rendered":"Le chlorhydrate d\u2019amitriptyline est-il stable dans Pentravan\u00ae ? Quelle est la m\u00e9thode de pr\u00e9paration ?"},"content":{"rendered":"<p>Dans le tableau de compatibilit\u00e9, vous trouverez toutes les informations sur la plage de dosage topique habituelle, le cosolvant le plus appropri\u00e9 et la stabilit\u00e9 physique ou chimique : <a href=\"https:\/\/www.fagron.be\/nl-be\/tools\" target=\"_blank\" title=\"Lien vers https:\/\/www.fagron.be\/nl-be\/tools\" rel=\"noopener\">https:\/\/www.fagron.be\/nl-be\/tools.<\/a><br \/>\nDans le tableau de compatibilit\u00e9, le chlorhydrate d\u2019amitriptyline \u00e0 2 % est indiqu\u00e9 comme non compatible. L\u2019exp\u00e9rience du march\u00e9 belge nous montre toujours que des concentrations plus importantes seraient possibles. Entre-temps, Fagron a mis en place les \u00e9tudes n\u00e9cessaires pour approfondir cette compatibilit\u00e9.  <\/p>\n<p>Le protocole g\u00e9n\u00e9ral de pr\u00e9paration se trouve sur www.fagron.be sur la page produit Pentravan\u00ae : <a href=\"https:\/\/www.fagron.be\/nl-be\/pentravan\" target=\"_blank\" title=\"Lien vers https:\/\/www.fagron.be\/nl-be\/pentravan\" rel=\"noopener\">https:\/\/www.fagron.be\/nl-be\/pentravan.<\/a> Pentravan\u00ae contient d\u00e9j\u00e0 de l\u2019eau. L\u2019ajout d\u2019une quantit\u00e9 suppl\u00e9mentaire d\u2019eau ne sera n\u00e9cessaire qu\u2019\u00e0 des concentrations plus \u00e9lev\u00e9es de l\u2019ingr\u00e9dient actif. <\/p>\n<p>Remarque : le chlorhydrate d\u2019amitriptyline est un zwitterion (= mol\u00e9cule avec un nombre \u00e9gal de groupes fonctionnels charg\u00e9s positivement et n\u00e9gativement). Cela permet \u00e0 la pr\u00e9paration de devenir plus liquide. Vous pouvez pr\u00e9server la viscosit\u00e9 de la pr\u00e9paration en ajoutant une petite quantit\u00e9 (q.s.) de polysorbate.  <\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false},"product_cat":[64],"faq-type":[2790],"grondstof":[3924],"qanda-related":[4060],"cnk":[3926,3928,3929,5254],"qanda-similar":[3930],"class_list":["post-60359","qanda","type-qanda","status-publish","hentry","product_cat-preparations-semi-solides","faq-type-question-de-preparation","grondstof-chlorhydrate-damitriptyline","qanda-related-pentravan-fr","cnk-0282947-fr","cnk-1023589-fr","cnk-4764361-fr","cnk-4849212-fr","qanda-similar-chlorhydrate-damitriptyline"],"acf":[],"_links":{"self":[{"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/qanda\/60359","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/qanda"}],"about":[{"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/types\/qanda"}],"wp:attachment":[{"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/media?parent=60359"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/product_cat?post=60359"},{"taxonomy":"faq-type","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/faq-type?post=60359"},{"taxonomy":"grondstof","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/grondstof?post=60359"},{"taxonomy":"qanda-related","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/qanda-related?post=60359"},{"taxonomy":"cnk","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/cnk?post=60359"},{"taxonomy":"qanda-similar","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/qanda-similar?post=60359"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}