{"id":48613,"date":"2024-09-05T10:00:58","date_gmt":"2024-09-05T08:00:58","guid":{"rendered":"https:\/\/fagroncompoundingservices.be\/qanda\/locoid-crelo-is-discontinued-est-il-un-protocole-de-preparation-disponible-pour-traiter-l-acetate-d-d-hydrocortisone-en-une-emulsion\/"},"modified":"2024-09-05T10:00:58","modified_gmt":"2024-09-05T08:00:58","slug":"locoid-crelo-is-discontinued-est-il-un-protocole-de-preparation-disponible-pour-traiter-l-acetate-d-d-hydrocortisone-en-une-emulsion","status":"publish","type":"qanda","link":"https:\/\/fagroncompoundingservices.be\/fr\/qanda\/locoid-crelo-is-discontinued-est-il-un-protocole-de-preparation-disponible-pour-traiter-l-acetate-d-d-hydrocortisone-en-une-emulsion\/","title":{"rendered":"Locoid crelo est en faillite.\nExiste-t-il un protocole de pr\u00e9paration pour incorporer de l\u2019ac\u00e9tate d\u2019hydrocortisone dans une \u00e9mulsion ?"},"content":{"rendered":"<p>La composition de Locoid Crelo \u00e9tait la suivante : hydrocortisone-17-butyrate 0,1 %, c\u00e9tomacrogol 1000, alcool c\u00e9tost\u00e9arylique, vaseline blanche, paraffine solide, huile de bernage, hydroxytolu\u00e8ne butyl\u00e9, propyl\u00e8ne glycol, citrate de sodium, acide citrique, hydroxybenzoate propyl\u00e9, hydroxybenzoate butyl\u00e9 et eau purifi\u00e9e.<br \/>\nL\u2019ingr\u00e9dient actif est la forme butyrate, qui n\u2019est pas disponible en tant que mati\u00e8re premi\u00e8re.<br \/>\nAinsi, seule une alternative \u00e0 l\u2019act\u00e9tate d\u2019hydrocortisone peut \u00eatre propos\u00e9e, mais celle-ci est beaucoup moins bien absorb\u00e9e par la peau : P (cm\/h) PC Hydrocortisone 1,6 x 10 -4 1,4 Hydrocortisone-21-ac\u00e9tate 1,7 x 10- 3 27 Hydrocortisone-21-propionate 9,8 x 10- 3 95 Hydrocortisone-21-butyrate 4,3 x 10-2 300 (P = coefficient de perm\u00e9abilit\u00e9 d\u00fb \u00e0 une peau isol\u00e9e et PC le coefficient de partage entre l\u2019\u00e9ther et l\u2019eau,  qui est une mesure de la lipophilie) De plus, une forme ester diff\u00e9rente d\u2019un cortico\u00efde a souvent une efficacit\u00e9 diff\u00e9rente.<br \/>\nIl est recommand\u00e9 de contacter le m\u00e9decin prescripteur.<br \/>\nLa base d\u2019\u00e9mulsion non ionique peut \u00eatre utilis\u00e9e comme base.      <\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false},"product_cat":[64],"faq-type":[2790],"grondstof":[4712],"qanda-related":[4239,4713],"cnk":[4715,4716,4717,4714],"qanda-similar":[4718],"class_list":["post-48613","qanda","type-qanda","status-publish","hentry","product_cat-preparations-semi-solides","faq-type-question-de-preparation","grondstof-acetate-dhydrocortisone","qanda-related-base-demulsion-non-ionique-mfs9","qanda-related-hydrocortisone","cnk-0274381-fr","cnk-0274399-fr","cnk-0274407-fr","cnk-2326627-fr","qanda-similar-acetate-dhydrocortisone"],"acf":[],"_links":{"self":[{"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/qanda\/48613","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/qanda"}],"about":[{"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/types\/qanda"}],"wp:attachment":[{"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/media?parent=48613"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/product_cat?post=48613"},{"taxonomy":"faq-type","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/faq-type?post=48613"},{"taxonomy":"grondstof","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/grondstof?post=48613"},{"taxonomy":"qanda-related","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/qanda-related?post=48613"},{"taxonomy":"cnk","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/cnk?post=48613"},{"taxonomy":"qanda-similar","embeddable":true,"href":"https:\/\/fagroncompoundingservices.be\/fr\/wp-json\/wp\/v2\/qanda-similar?post=48613"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}